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Issue 02/2026: Sweet paradox.

Fact check: How much of our brain do we actually use?

Text: Georg Keller

Do we really use only 10 percent of our brain? Neuroscience shows that we use all of it. Its capacity to learn and adapt—known as neuroplasticity—is where its true potential lies, and physical activity can help.

Illustration of a woman standing on a leader painting a huge image of a brain
(Illustration: Kathrin Bänziger)

The claim that people use only 10 percent of their brain has been scientifically disproven. Indeed, imaging techniques such as functional magnetic resonance imaging (fMRI) show that almost all areas of the brain are active even during simple activities or sleep. The myth emerged in the late 19th and early 20th century, with the psychologist William James writing in around 1908 that people use just a fraction of their mental and physical resources. Although he never specified a percentage, the 10-percent claim was later attributed to him.

Brain activity: Why coordination matters

In disorders of brain function, such as schizophrenia, the problem can stem from an excess of uncoordinated activity. One example is the “default mode network” — a network that is active especially while we are at rest and that, in healthy individuals, is downregulated during focused activities. In people with schizophrenia, the network often remains active, leading to an overlap between internal thought processes and external information processing. Likewise, acoustic hallucinations can be attributed to uncontrolled activity in the auditory cortex, which the brain wrongly interprets as external stimuli. Rather than a lack of activity, the problem here is a lack of coordination.


Original publication

Annual Review of Neuroscience (2024), doi: 10.1146/annurev-neuro-100223-121214

Georg Keller is a neurobiologist and research group leader at the Friedrich Miescher Institute for Biomedical Research. He researches how brain networks are affected by psychiatric treatments.


More articles in this issue of UNI NOVA (November 2026). 

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