Complex reaction cascades can be triggered in artificial molecular systems: Swiss scientists have constructed an enzyme than can penetrate a mammalian cell and accelerate the release of a hormone. This then activates a gene switch that triggers the creation of a fluorescent protein. The findings were reported by researchers from the NCCR Molecular Systems Engineering, led by the University of Basel and ETH Zurich.
Marek Basler, Professor at the Biozentrum of the University of Basel, is one of the two recipients of the 2018 EMBO Gold Medal. The European Molecular Biology Organization (EMBO) has recognized the researcher for his outstanding scientific achievements in the field of infection biology.
A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria. Changing metabolic states of the microbes have an effect on defense cells at different stages of alert or rest, as researchers from the Department of Biomedicine at the University and University Hospital of Basel report in the journal "Mucosal Immunology."
For 250 years, the extensive set of manuscripts and papers lay in the University Library’s basement. Now, linguists from the University of Basel are providing access to Johann Jakob Spreng’s Grosses Glossarium der deutschen Sprache (Great Glossary of the German Language) for the first time.
A medicinal plant frequently used in Traditional Chinese Medicine (TCM) – Evodia rutaecarpa – contains substances that can cause cardiac arrhythmia. This is what researchers from the Universities of Basel, Vienna and Utrecht have recently found out.
Physicists from the University of Basel have observed the quantum mechanical Einstein-Podolsky-Rosen paradox in a system of several hundred interacting atoms for the first time. The phenomenon dates back to a famous thought experiment from 1935. It allows measurement results to be predicted precisely and could be used in new types of sensors and imaging methods for electromagnetic fields.
The research group of Alex Schier, Director of the Biozentrum, University of Basel, has investigated more closely how a single embryonic cell develops into a heart, nerve or blood cell. For the first time, the researchers have been able to reconstruct the developmental trajectories of individual embryonic cells. Their results also suggest that cells can change their path during their maturation process.
Imaging techniques can be used to detect the development of psychosis in the brains of high-risk patients at an early stage, as reported by researchers from the University of Basel and Western University in the journal JAMA Psychiatry.
Economist Mattia Fochesato researches the factors that influence income and asset distribution in the long term. The President’s Board of the University of Basel has appointed him as the Faculty of Business and Economics’s new Assistant Professor in Quantitative Economic History/Cliometrics. The five-year professorship is financed by the Max Geldner Foundation.
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.