Gentler cell therapies for blood cancer and other serious blood diseases – this is the goal that Cimeio Therapeutics, a University of Basel spin-off, has set itself. The start-up has been able to make a great step forward together with a company that offers a pioneering method for the targeted editing of genes.
Using a new technique, researchers at the University of Basel have succeeded in cooling a small membrane down to temperatures close to absolute zero using only laser light. Such extremely cooled membranes could, for instance, find applications in highly sensitive sensors.
Infections are among the most frequent complications during a hospital stay. Researchers at the University of Basel have now uncovered why one of the most dangerous nosocomial pathogens is so difficult to combat. It follows a dual strategy, with some bacteria colonizing the tissue surface while others spread in the body. The study provides important insights into the infection process and opens up new ways to treat infections.
Meat, milk, labor: domestic cattle have a lot to offer. Their history is consequently closely intertwined with that of humankind. Researchers at the University of Basel have investigated the genetic development of this livestock animal in Switzerland, and it is linked with societal developments.
Bacteria harness the power of communities. A research group at the University of Basel has now discovered that the bacterial pathogen that causes cholera forms a novel type of bacterial community on immune cells: an aggressive biofilm that is lethal for the cells. The study, recently published in the journal Cell, provides new insights into the infection strategies of pathogens.
Breast cancer spreading to other organs usually heralds a poorer prognosis. Researchers at the University and University Hospital of Basel have discovered a process that helps breast cancer cells implant themselves in certain places in the body. The results suggest a way of preventing secondary tumors.
Receptor proteins serve as the “eyes and ears” of the cell. The largest receptor family are the so-called G protein-coupled receptors. They respond to highly diverse stimuli ranging from photons to hormones and odorants. Researchers at the University of Basel have discovered a unique recognition pattern that works like a barcode and tags the receptor for desensitization. By this mechanism, signaling in cells is rapidly switched off when it is no longer needed.
Nanomedicine involves packaging drugs in microscopic particles to make them more effective. Nanopharmacy professor Scott McNeil explains the opportunities presented by the new technology and what is still holding it back: approval procedures, for example, as seen in the inconsistent approach taken with the Covid-19 vaccines.
In March 2022, Microsoft published research results about the realisation of a special type of particle that might be used to make particularly robust quantum bits. Researchers at the University of Basel are now calling these results about so-called Majorana particles into doubt: through calculations they have shown that the findings can also be explained differently.