Just like an acrobatic duo, some proteins lend each other stability. Researchers at the Biozentrum of the University of Basel have discovered that the protein “Trigger factor” recognizes a partner by instable, flexible domains, to then together form a stable protein duo.
Nine research projects involving Basel-based researchers in the field of personalized health will receive more than CHF 14 million over the next three years.
Around a third of all employees find their work stressful. Interventions for stress and burnout are available, but often not accessible for many employees. A self-help book based on Acceptance and Commitment Therapy (ACT) has the potential to reduce burnout, stress and symptoms of depression – without any therapist contact.
New findings will help to identify the genetic causes of brain disorders: researchers at the Universities of Basel, Bonn and Cologne have presented a systematic catalog of specific variable locations in the genome that influence gene activity in the human hippocampus, as they report in the journal Nature Communications.
Inflammation processes are responsible for the failure of insulin production in diabetes patients. The patients’ own immune systems can contribute to treatment of this disease: researchers at the University of Basel and University Hospital Basel have found a feedback mechanism that could help maintain insulin production in overweight sufferers, as they report in the journal Immunity.
Children and adolescents regularly confronted with violence in their community have a greater tendency to show antisocial behavior. This finding was reported by researchers from the University of Basel and the University Psychiatric Hospital Basel. Their new study examined the link between exposure to community violence and antisocial behavior in over 1000 children and adolescents from seven European countries.
Extracellular polysaccharides play a central role in the survival capabilities of caries-causing bacteria in dental plaque, report researchers from the University of Basel’s Preventative Dentistry and Oral Microbiology Clinic and Department of Biomedical Engineering in the journal Plos One.
People differ in their willingness to take risks. An individual’s propensity for risk taking can also vary across domains. However, there is new evidence showing that there is also a general factor of individual risk preference, which remains stable over time – akin to the general Intelligence Quotient (IQ).
Cancer cells can reactivate a cellular process that is an essential part of embryonic development. This allows them to leave the primary tumor, penetrate the surrounding tissue and form metastases in peripheral organs.