Many psychiatric disorders are accompanied by memory deficits. Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.
Physicists at the University of Basel have observed a spontaneous magnetic order of electron and nuclear spins in a quantum wire at temperatures of 0.1 kelvin. In the past, this was possible only at much lower temperatures, typically in the microkelvin range. The coupling of nuclei and electrons creates a new state of matter whereby a nuclear spin order arises at a much higher temperature. The results are consistent with a theoretical model developed in Basel a few years ago.
Motor commands issued by the brain to activate arm muscles take two different routes. As a research group at the University of Basel's Biozentrum and the Friedrich Miescher Institute for Biomedical Research has now discovered, many neurons in the spinal cord send their instructions not only towards the musculature, but at the same time also back to the brain via an exquisitely organized network.
A research group at the Biozentrum of the University of Basel has discovered an amino acid signal essential for error-free cell division. This signal regulates the number of centrosomes in the cell, and its absence results in the development of pathologically altered cells. Remarkably, such altered cells are found in people with a neurodevelopmental disorder, called autosomal recessive primary microcephaly.
Neurons transmit information with the help of special channels that allow the passage of potassium ions. Defective potassium channels play a role in epilepsy and depression. The scientists working with Prof. Henning Stahlberg at the Biozentrum of the University of Basel have now identified the complete 3D structure of a particular potassium channel, a HCN channel. This enabled them to draw conclusions about its mechanism of action.
Prospective students interested in pursuing a degree in dental medicine should not only show interest for the medical matters but also need to possess superior manual dexterity skills. A new online self-assessment offers prospective students the opportunity to test and analyze their manual skills.
The life-threatening disease typhoid fever results from the ongoing battle between the bacterial pathogen Salmonella and the immune cells of the body. Prof. Dirk Bumann’s research group at the Biozentrum of the University of Basel has now uncovered how the typhoid pathogen repeatedly manages to evade the host’s immune system.