Ludwig Kappos awarded John Dystel Prize for MS Research
Neurologist Prof. emeritus Dr. Ludwig Kappos has been awarded the 2026 John Dystel Prize for Multiple Sclerosis Research – one of the most prestigious honors in the field of multiple sclerosis research.
19 March 2026
The prize recognizes his outstanding and pioneering contributions to the study and treatment of multiple sclerosis (MS). Over several decades, Kappos has played a decisive role in advancing modern therapies and has had a lasting impact on clinical research in the field of neuroimmunology.
Kappos has been involved in clinical trials that established the safety and efficacy of nearly all disease-modifying MS therapies available today. These therapies have fundamentally expanded and improved treatment options for people living with MS. In addition, he has made important contributions to the standardization of methods for measuring disease progression and disability, in particular to the further development of the Expanded Disability Status Scale (EDSS), as well as to the establishment of magnetic resonance imaging (MRI) as a central tool in research and clinical practice.
The official award ceremony will take place on April 19, 2026, at the Annual Meeting of the American Academy of Neurology in Chicago (USA), where Ludwig Kappos will also deliver the Dystel Prize Lecture.
In recent years, Kappos has also made significant contributions to the understanding of disease mechanisms, particularly to the concept of progression independent of relapse activity (PIRA). His work has shown that many people with MS accumulate disability even in the absence of acute relapses – a finding that has fundamentally changed how the disease is studied and treated.
Until his retirement in 2020, Ludwig Kappos was Professor of Neurology at the University of Basel and Head Physician at the University Hospital Basel. Since 2019, he has been leading the Research Center for Clinical Neuroimmunology and Neuroscience Basel RC2NB.
The John Dystel Prize has been awarded jointly by the National MS Society and the American Academy of Neurology since 1994 and is endowed with 40,000 US dollars. It recognizes outstanding research contributions that have led to significant advances in the understanding, prevention, or treatment of multiple sclerosis.
