Biological membranes are like a guarded border. They separate the cell from the environment and at the same time control the import and export of molecules. The nuclear membrane can be crossed via many tiny pores. Scientists at the Biozentrum and the Swiss Nanoscience Institute at the University of Basel, together with an international team of researchers, have discovered that proteins found within the nuclear pore function similar to a velcro. In Nature Nanotechnology they report how these proteins can be used for controlled and selective transport of particles.
Schaulager is currently hosting the most extensive exhibit to date of works by the artist Paul Chan. A visit to the exhibit together with Laurenz professor Dr. Susanne Leeb, who organized a joint seminar together with Chan.
During evolutionary diversification of vertebrate limbs, the number of toes in even-toed ungulates such as cattle and pigs was reduced and transformed into paired hooves. Scientists at the University of Basel have identified a gene regulatory switch that was key to evolutionary adaption of limbs in ungulates. The study provides fascinating insights into the molecular history of evolution and is published by Nature today.
Spiders are traditionally viewed as predators of insects. Zoologists from Switzerland and Australia have now published a study that shows: spiders all over the world also prey on fish. The academic journal Plos One has just published the results.
T cells use a novel mechanism to fight leukemia. They may recognize unique lipids produced by cancer cells and kill tumor cells expressing these lipid molecules. A study conducted by researchers at the University of Basel shows that a tumor-associated lipid stimulates specific T cells, which efficiently kill leukemia cells both in vitro and in animal models.
After initially visiting a school psychologist, adolescents in the United States with a mental disorder often go to seek care from their pediatricians or family doctors. Fewer of them continue their treatment directly with a psychotherapist or doctor specialized in mental disorders. This shows an analysis conducted by scientists at the University of Basel that has just been published in the academic journal Plos One. The results are based on a nationally representative cohort of 6,500 U.S. teenagers.
A new method allows calcified and constricted blood vessels to be visualized with micrometer precision, and can be used to design containers for targeted drug delivery. Within the project “NO-stress”, materials scientists from the Medical Faculty of the University of Basel combined cutting-edge-imaging techniques to visualize and quantify the constrictions caused by atherosclerosis.
A tiny nanoscale syringe is Salmonella’s weapon. Using this, the pathogen injects its molecular agents into the host cells and manipulates them to its own advantage. A team of scientists at the Biozentrum of the University of Basel demonstrate in their current publication in Cell Reports that a much investigated protein, which plays a role in Salmonella metabolism, is required to activate these needles and makes the replication and spread of Salmonella throughout the whole body possible.
Who had the privilege to spend eternal life next to the pharaoh? Close to the royal tombs in the Egyptian Valley of the Kings, excavations by Egyptologists from the University of Basel have identified the burial place of several children as well as other family members of two pharaohs.